במחקר זה, השווינו את השכיחות של MGD בקרב מרכיבי עדשות מגע רכות לעומת קבוצת ביקורת. בנוסף, השווינו את השכיחות של MGD בקרב מרכיבי עדשות מגע רכות לעומת נבדקים שרכשו עדשות ללא בדיקת התאמה מקדימה. כמו כן חיפשנו קורלציה בין בדיקות אובייקטיביות לסובייקטיביות באבחון MGD.

שם המנחה: גברת רעות יפרח

Introduction: Meibomian gland dysfunction (MGD) has been associated with cessation of contact lens (CL) wear, though the relationship between CL wear and MGD is inconclusive. This study compared the prevalence of MGD among fitted soft CL wearers (FIT), over-the-counter (OTC) soft CL wearers and non-CL (NCL) wearing controls.

Methods: Healthy subjects (ages 18-50) performed habitual LogMAR visual acuity, non-invasive tear break-up time (NITBUT), TBUT, Schirmer test, Efron grading scale, Meibum Quality Score (MQS), Meibum Expressibility Score (MES), Cobra HD meibography, Dry eye (DE) symptoms and Ocular Surface Disease Index (OSDI) score. Kruskal-Wallis test and Mann-Whitney U test were performed to compare between groups (only on the R eye).

Results: 128 subjects (ages 18-39, 75% females);30 FIT (mean age:22.3±3.1), 42 OTC (mean age: 23.0±4.7) and 56 NCL (mean age: 22.2±3.5) participated in this study. NITBUT, TBUT, Schirmer tests, Efron MGD grading, MES, MG lower eyelids loss and OSDI were similar between groups. The Efron scale limbal redness, conjunctivitis, corneal and conjunctival staining were significantly worse in CL wearers, with conjunctival staining worse in OTC compared to FIT (p<0.02). MQS was significantly better for the NCL (0.2±0.5) compared to OTC (0.8±0.9, p<0.01). MG upper eyelids loss was significantly lower in NCL (12.2±8.5) compared with FIT (19.3±12.7, p<0.01) and OTC (17.4±8.5, p<0.001). More DE symptoms was found in OTC (3.6±2.4) compared to NCL (2.3±2.1, p<0.01).

Conclusions: There are more signs and symptoms of MGD in CL wearers than NCL, stressing the importance in fitting and monitoring of CL wearers.