Introduction
Keratoconus (KC) is a corneal disorder which leads to myopia, irregular astigmatism and eventually visual impairment (Zabala, Archila, 1988). Several terms have been put forward to describe different forms of early KC when biomicroscopic signs are absent, including KC suspect (McMonnies, 2014). Patients with KC usually do not apply for Photorefractive keratectomy (PRK) surgery; however KC suspect patients often have PRK surgery. This study will evaluate the visual outcomes of KC suspect patients after PRK surgery in comparison to normal controls.
Methods
This retrospective study recruited subjects (18-35 years old) from Care Laser Clinics who underwent PRK surgery (2014-2015). KC suspect and normal status was determined by Sirius imaging. Demographic information and BCVA before and after surgery were retrieved anonymously from patient records. The safety index (BCVA post /BCVA pre) and efficiency index (UCVA post /BCVA pre) were calculated. Student t-test was used to test significance.
Results
46 KC suspect and 50 normal controls participated in the study (mean age of 24.67±4.58). BCVA pre and post-surgery (KC suspect: 0.93±0.09, 0.99±0.11; control: 0.90±0.12, 1.02± 0.17 respectively; p=0.28) and Safety Index (1.07±0.17, 1.14±0.19 for KC suspects and normal respectively; p=0.07) was not different between groups. However, Efficiency Index was higher for normal controls (p<0.001).
Conclusion
The results of this study are ambiguous. More research is required perhaps with a larger cohort of subjects.